what does "kick in " mean?

When something kicks in, it begins to operate or have an effect. For instance, if a law kicks in, you have to start obeying it. If you are sick, you might start to get better once your medicine kicks in. Or if an emotion kicks in, you suddenly start to feel it.

Has anything new kicked in for you recently?

"WHEN I WAS IN THE USA, I HAD A LIME DEASE, SO I HAD TO GO TO THE HOSPITAL!they prescribed me an antibiotic" "THE MEDECINE HAD A SIDE EFFECT, IT MADE ME SLEEPY, BUT IT HADN´T KICKED IN TILL THE NEXT DAY"

Portuguese translation: to Kick in: fazer efeito!